Laurent Drouot Selected Research

Signal Recognition Particle

1/2019	In vivo pathogenicity of IgG from patients with anti-SRP or anti-HMGCR autoantibodies in immune-mediated necrotising myopathy.
1/2018	Necrosis in anti-SRP+ and anti-HMGCR+myopathies: Role of autoantibodies and complement.
1/2016	High risk of cancer in autoimmune necrotizing myopathies: usefulness of myositis specific antibody.
5/2014	Serum levels of anti-SRP54 antibodies reflect disease activity of necrotizing myopathy in a child treated effectively with combinatorial methylprednisolone pulses and plasma exchanges followed by intravenous cyclophosphamide.
7/2011	Correlation of anti-signal recognition particle autoantibody levels with creatine kinase activity in patients with necrotizing myopathy.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Laurent Drouot Research Topics

Disease

9	Muscular Diseases (Myopathy) 01/2019 - 07/2011
7	Myositis (Idiopathic Inflammatory Myopathies) 01/2019 - 07/2011
6	Pemphigus (Pemphigus Vulgaris) 01/2022 - 06/2005
4	Autoimmune Diseases (Autoimmune Disease) 10/2021 - 10/2002
4	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 08/2015 - 10/2002
3	COVID-19 12/2021 - 01/2020
2	Neoplasms (Cancer) 01/2019 - 01/2016
2	Dermatomyositis (Dermatopolymyositis) 01/2019 - 01/2016
2	Vesiculobullous Skin Diseases (Subcorneal Pustular Dermatosis) 11/2008 - 11/2006
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2005 - 08/2002
1	Pathologic Complete Response 01/2022
1	Necrosis 01/2018
1	Atrophy 04/2017
1	Fecal Incontinence 01/2015
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2015
1	Muscle Weakness 01/2014
1	Gliosis 01/2013
1	Hypergammaglobulinemia (Hyperimmunoglobulinemia) 07/2011
1	Foreign-Body Reaction 05/2011
1	Inflammation (Inflammations) 05/2011
1	Foreign Bodies (Foreign Body) 05/2011
1	Bullous Pemphigoid (Pemphigoid) 11/2008
1	Genetic Predisposition to Disease (Genetic Predisposition) 11/2006
1	Skin Diseases (Skin Disease) 09/2006
1	Hepatocellular Carcinoma (Hepatoma) 10/2005
1	Primary Ovarian Insufficiency 03/2003
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2003
1	Rheumatic Diseases (Rheumatism) 08/2002
1	Connective Tissue Diseases (Connective Tissue Disease) 08/2002
1	Rheumatoid Arthritis 08/2002
1	Vasculitis (Vasculitides) 08/2002

Drug/Important Bio-Agent (IBA)

12	AutoantibodiesIBA 10/2021 - 08/2002
11	AntibodiesIBA 10/2021 - 08/2002
6	Immunoglobulin G (IgG)IBA 01/2022 - 11/2008
6	Proteins (Proteins, Gene)FDA Link 10/2021 - 10/2002
5	Signal Recognition ParticleIBA 01/2019 - 07/2011
5	Oxidoreductases (Dehydrogenase)IBA 01/2019 - 01/2014
3	AntigensIBA 11/2008 - 08/2002
3	Desmoglein 1IBA 11/2006 - 06/2005
2	Rituximab (Mabthera)FDA Link 01/2022 - 01/2015
2	DesmogleinsIBA 10/2021 - 11/2008
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 02/2014
2	Creatine Kinase (Creatine Phosphokinase)IBA 01/2019 - 07/2011
2	Complement System Proteins (Complement)IBA 01/2018 - 01/2014
2	CytokinesIBA 04/2017 - 10/2005
2	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2014 - 05/2011
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2014 - 01/2014
2	AutoantigensIBA 11/2006 - 09/2006
2	Peptides (Polypeptides)IBA 11/2006 - 08/2002
1	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2021
1	Polysaccharides (Glycans)IBA 10/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2017
1	InterleukinsIBA 04/2017
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 04/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2017
1	Infliximab (Remicade)FDA Link 08/2015
1	Ligases (Synthetase)IBA 01/2015
1	Antiphospholipid AntibodiesIBA 11/2014
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 05/2014
1	Methylprednisolone FDA LinkGeneric 05/2014
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 01/2014
1	Histocompatibility Antigens Class IIBA 09/2013
1	SiliconesIBA 05/2011
1	Toll-Like Receptor 4IBA 05/2011
1	envoplakinIBA 11/2008
1	Protein Isoforms (Isoforms)IBA 11/2006
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 11/2006
1	LipopolysaccharidesIBA 10/2005
1	Conditioned Culture MediaIBA 10/2005
1	PhosphoproteinsIBA 01/2005
1	NucleophosminIBA 01/2005
1	Cardiolipins (Cardiolipin)IBA 01/2005
1	calpastatinIBA 08/2002
1	Complementary DNA (cDNA)IBA 08/2002

Therapy/Procedure

3	Therapeutics 05/2014 - 07/2011
2	Transplantation 01/2021 - 01/2013
1	Aftercare (After-Treatment) 01/2022
1	Kidney Transplantation 12/2021
1	Renal Dialysis (Hemodialysis) 01/2021
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2015
1	Plasma Exchange 05/2014
1	Lasers (Laser) 07/2011
1	Prostheses and Implants (Prosthesis) 05/2011